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Symbol
Name
ID
Nrg1
neuregulin 1
MGI:96083
Phenotype annotations related to cardiovascular system
*Aspects of the system are reported to show a normal phenotype.
Darker colors indicate more annotations

Mouse Phenotypes
cardiovascular system phenotype
abnormal myocardium layer morphology
absent trabeculae carneae
trabecula carnea hypoplasia
abnormal atrioventricular cushion morphology
failure of atrioventricular cushion closure
abnormal heart morphology
decreased heart weight
enlarged heart
abnormal heart ventricle morphology
thin ventricular wall
dilated heart ventricle
enlarged pericardium
abnormal cardiovascular system physiology
decreased cardiac output
poor circulation
decreased cardiac muscle contractility
decreased ventricle muscle contractility
decreased left ventricle systolic pressure
decreased heart rate
irregular heartbeat
Availability Mouse Genotype
Nrg1tm1Cbm/Nrg1tm1Cbm
Nrg1tm1Gne/Nrg1tm1Gne
Nrg1tm1Leth/Nrg1tm1Leth
Nrg1tm1Zhou/Nrg1tm1Zhou *
Nrg1tm2Cbm/Nrg1tm2Cbm
Nrg1tm2Zhou/Nrg1tm2Zhou
Nrg1tm1Cbm/Nrg1+

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory